Small vs large airliners

Would it be more profitable in-game to fill the same number on a short-haul high capacity flight using say 100 frequencies on a 737 or 30 frequencies on a 777? Which would you guys prefer to use?

I would imagine using large aircraft would save a bit more money, especially throwing in wage and turnaround related costs but why is it that real airlines are moving away from the large airliners? Is it to spread out the risks more or give the airlines more flexibility?

To me, the 737 is better. They're cheaper to operate, and they reward you handsomely.

Smaller aircraft are cheaper to purchase an operate, but you will have to buy more 737s to carry the same amount of pax as a 777. If you're flying long-haul, the 777 is the better option, but for short-medium haul stick with narrow-body airliners as they turn around faster and enable you to offer more frequencies and more on-time flights which leads to higher ratings. I use the 737 series or the A320 family for most of my airlines.

Would it be more profitable in-game to fill the same number on a short-haul high capacity flight using say 100 frequencies on a 737 or 30 frequencies on a 777? Which would you guys prefer to use?

I would imagine using large aircraft would save a bit more money, especially throwing in wage and turnaround related costs but why is it that real airlines are moving away from the large airliners? Is it to spread out the risks more or give the airlines more flexibility?

The reason why real airlines prefer to reduce size rather than frequency on short haul routes is that business travelers on these routes like to have a high amount of flexibility with scheduling. 10 daily flights gives you many more options than 4.